Metabolic Syndrome Management: Strategies for Early Detections and Preventive Interventions / (Record no. 614597)

000 -LEADER
fixed length control field 02029nam a22001577a 4500
082 ## - DEWEY DECIMAL CLASSIFICATION NUMBER
Classification number 610
100 ## - MAIN ENTRY--PERSONAL NAME
Personal name Rehman, Sanam
245 ## - TITLE STATEMENT
Title Metabolic Syndrome Management: Strategies for Early Detections and Preventive Interventions /
Statement of responsibility, etc. Sanam Rehman
264 ## - PRODUCTION, PUBLICATION, DISTRIBUTION, MANUFACTURE, AND COPYRIGHT NOTICE
Place of production, publication, distribution, manufacture Islamabad :
Name of producer, publisher, distributor, manufacturer SMME- NUST;
Date of production, publication, distribution, manufacture, or copyright notice 2025.
300 ## - PHYSICAL DESCRIPTION
Extent 67p.
Other physical details Soft Copy
Dimensions 30cm
500 ## - GENERAL NOTE
General note The prediction and management of metabolic syndrome (MetS) is crucial due to its chronic<br/>nature and global health challenge. This study aims for early and accurate MetS diagnosis<br/>for timely prevention by managing associated risk factors. It utilizes machine learning<br/>(ML) and deep learning (DL) techniques while considering demographic and ethnic<br/>variability. Notably, there is a lack of MetS prediction research in the Pakistani population,<br/>which has unique genetic and lifestyle diversity. This study addresses this gap using a<br/>dataset of 502 individuals from five Pakistani cities (MetS prevalence = 43.4%), with 24<br/>features from anthropometric, clinical, lifestyle, and family history data. It is the first study<br/>evaluating fifteen classifiers (12 ML and 3 DL models) through five-fold cross-validation.<br/>AdaBoost outperformed with 93.4% accuracy, an Area under Curve (AUC) of 0.97, and pvalue < 0.05. Feature importance analysis (Permutation and SHAP) identified fasting blood<br/>glucose, systolic blood pressure, triglycerides, and obesity as key biomarkers for MetS.<br/>Odds ratio analysis across gender and age groups (95% CI) showed that Body Mass Index<br/>(BMI), blood pressure, and glucose levels were strongly associated with MetS in aging<br/>males, while glucose and HDL were more influential in older females. This study provides<br/>population-specific insights into MetS risk, enhancing early prediction accuracy and<br/>enabling targeted interventions for high-risk individuals.
650 ## - SUBJECT ADDED ENTRY--TOPICAL TERM
Topical term or geographic name entry element MS Biomedical Sciences (BMS)
700 ## - ADDED ENTRY--PERSONAL NAME
Personal name Supervisor : Dr. Ahmed Fuwad
856 ## - ELECTRONIC LOCATION AND ACCESS
Uniform Resource Identifier <a href="http://10.250.8.41:8080/xmlui/handle/123456789/54549">http://10.250.8.41:8080/xmlui/handle/123456789/54549</a>
942 ## - ADDED ENTRY ELEMENTS (KOHA)
Source of classification or shelving scheme
Koha item type Thesis
Holdings
Withdrawn status Permanent Location Current Location Shelving location Date acquired Full call number Barcode Koha item type
  School of Mechanical & Manufacturing Engineering (SMME) School of Mechanical & Manufacturing Engineering (SMME) E-Books 08/29/2025 610 SMME-TH-1151 Thesis
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