Development and Characterization of DNA-based Kit for Cancer Diagnosis / Areej Fatima
Material type:
TextIslamabad : SMME- NUST; 2023Description: 74p. ; Soft Copy 30cmSubject(s): MS Biomedical Sciences (BMS)DDC classification: 610 Online resources: Click here to access online Summary: Cancer impermanence and the incidence rate is increasing gradually. Cancer costs us not only
economically but also our beloved ones. Different treatments are available to combat cancer
propagation. The effectiveness of the treatment is directly related to the diagnosis of cancer. The
earlier the cancer diagnosis, the earlier the treatment begins. Various types of diagnostic methods
for cancer are available, but all those deal with the later stages of cancer. Moreover, they are
specific to one type of cancer. In this study, we tried to design a biosensor that can detect cancer
at its earlier stages. The biosensor simply consists of graphene that acts as a transistor, a linker that
makes the connection between the graphene and antibodies that capture the biomarker of cancer.
Metal electrodes are present at both ends of the graphene. We immobilized the antibodies on the
sensor, but we haven’t attained the current-voltage shift produced in response to the binding of
cancer biomarkers to the antibodies. A lot remains yet to explore in this domain.
| Item type | Current location | Home library | Shelving location | Call number | Status | Date due | Barcode | Item holds |
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Thesis
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School of Mechanical & Manufacturing Engineering (SMME) | School of Mechanical & Manufacturing Engineering (SMME) | E-Books | 610 (Browse shelf) | Available | SMME-TH-882 |
Cancer impermanence and the incidence rate is increasing gradually. Cancer costs us not only
economically but also our beloved ones. Different treatments are available to combat cancer
propagation. The effectiveness of the treatment is directly related to the diagnosis of cancer. The
earlier the cancer diagnosis, the earlier the treatment begins. Various types of diagnostic methods
for cancer are available, but all those deal with the later stages of cancer. Moreover, they are
specific to one type of cancer. In this study, we tried to design a biosensor that can detect cancer
at its earlier stages. The biosensor simply consists of graphene that acts as a transistor, a linker that
makes the connection between the graphene and antibodies that capture the biomarker of cancer.
Metal electrodes are present at both ends of the graphene. We immobilized the antibodies on the
sensor, but we haven’t attained the current-voltage shift produced in response to the binding of
cancer biomarkers to the antibodies. A lot remains yet to explore in this domain.
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