Essential Oil (Eo) Blend Loaded Solid Lipid Nanoparticles (Slns) As Novel Deodorant / Zahra Rehman

By: Zahra Rehman, Zahra RehmanContributor(s): Supervisor : Dr. Nosheen Fatima RanaMaterial type: TextTextIslamabad : SMME- NUST; Description: 66p. Soft Copy 30cmSubject(s): MS Biomedical Sciences (BMS)DDC classification: 610 Online resources: Click here to access online
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Thesis Thesis School of Mechanical & Manufacturing Engineering (SMME)
School of Mechanical & Manufacturing Engineering (SMME)
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Human odors have been of great concern to society. The generation of malodor on the skin surface
of modern humans is caused by the biotransformation of naturally secreted non-odorous precursor
molecules into volatile odorants by members of the commensal microbiome. Culture-based
microbiological studies revealed that the axillary microbiota consists primarily of Gram-positive
bacteria of the genera Staphylococcus, Corynebacterium, and Propionibacterium. Currently there
is need to study the selective suppression of the growth of microorganisms involved in diseases
and unpleasant odors may result in the establishment of a good symbiotic relationship between
microorganisms and humans. As the growth of axillary microbiota which causes odor can be
controlled by several ways including hygiene and antimicrobial skin friendly essential oils. Given
the limitations in currently available products, a deodorant/antiperspirant formulation that
effectively prevents body odor without producing skin sensitivity or perceived undesirable
consequences is required. Our work is the deodorant production which is made from all naturally
extracted products which includes the lipid which sources from whale fish and is completely
alcohol and toxins free. This deodorant is fabricated using lecithin, solid lipid nanoparticles,
natural essential oils, and fragrance which are incorporated in a gel. The gel phase contains
triethanolamine, TEA and Carbopol-940. TEA is used in safer limits for the polymerization of
Carbopol-940 to form a clear gel. The essential oils used possess antibacterial properties which are
effective against sweat bacteria. The deodorant is aluminium and parabens free as they contribute
to cancer development and hormonal imbalance.

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