TY  - BOOK
AU  - Tariq, Faiza 
AU  - Supervisor : Dr. Adeeb Shehzad
TI  - Synthesis, Characterization and Application Of Natural Nano Composites
U1  - 610 
PY  - 2023///
CY  - Islamabad : 
PB  - SMME- NUST; 
KW  - MS Biomedical Sciences (BMS)
N1  - The use of natural polymers in the creation of skin wound dressings has gained attentionfor its potential to speed up healing and protect against pathogens. In this study, theability of the Papaver somniferum plant to heal wounds in various forms, suchas pureplant extract, plant-derived silver nanoparticles, and their inclusion in a polyvinyl alcohol
hydrogel, was investigated. Characterization of the compounds was done usingUVspectrophotometry, X-ray diffraction, Fourier transform infrared spectroscopy, scanningelectron microscopy, and energy dispersive spectroscopy. Antimicrobial tests showedthat silver nanoparticles had a zone of inhibition of 12mm against Staphylococcus aureus, while the silver nanoparticle hydrogel had a zone of inhibition of 23mmagainst Klebsillapneumonia. The zone of inhibition by the plant extract was 11mmagainst
Staphylococcus aureus, while the plant extract gel had a zone of inhibition of 16mmagainst Staphylococcus aureus. The results suggest that the bio-composite patches createdfrom these materials have potential to work against both gram-positive andgram-negative bacteria. In a mouse model, the wound healing capacity was highest for thesilver nanoparticle gel, with a wound closure of 1.7mm. Histological analysis alsoshowed that the silver nanoparticle hydrogel had excellent wound repair properties. Overall, the study suggests that pure AgNPs and bio-composite hydrogel of AgNPs haveefficient and quick healing of wounds as compared to the plant extract and plant nanocomposites hydrogel
UR  - http://10.250.8.41:8080/xmlui/handle/123456789/32415
ER  -