000			02306nam a22001577a 4500
082			_a610
100			_aZahra Rehman, Zahra Rehman _9121555
245			_aEssential Oil (Eo) Blend Loaded Solid Lipid Nanoparticles (Slns) As Novel Deodorant / _cZahra Rehman
264			_aIslamabad : _bSMME- NUST;
300			_a66p. _bSoft Copy _c30cm
500			_aHuman odors have been of great concern to society. The generation of malodor on the skin surface of modern humans is caused by the biotransformation of naturally secreted non-odorous precursor molecules into volatile odorants by members of the commensal microbiome. Culture-based microbiological studies revealed that the axillary microbiota consists primarily of Gram-positive bacteria of the genera Staphylococcus, Corynebacterium, and Propionibacterium. Currently there is need to study the selective suppression of the growth of microorganisms involved in diseases and unpleasant odors may result in the establishment of a good symbiotic relationship between microorganisms and humans. As the growth of axillary microbiota which causes odor can be controlled by several ways including hygiene and antimicrobial skin friendly essential oils. Given the limitations in currently available products, a deodorant/antiperspirant formulation that effectively prevents body odor without producing skin sensitivity or perceived undesirable consequences is required. Our work is the deodorant production which is made from all naturally extracted products which includes the lipid which sources from whale fish and is completely alcohol and toxins free. This deodorant is fabricated using lecithin, solid lipid nanoparticles, natural essential oils, and fragrance which are incorporated in a gel. The gel phase contains triethanolamine, TEA and Carbopol-940. TEA is used in safer limits for the polymerization of Carbopol-940 to form a clear gel. The essential oils used possess antibacterial properties which are effective against sweat bacteria. The deodorant is aluminium and parabens free as they contribute to cancer development and hormonal imbalance.
650			_aMS Biomedical Sciences (BMS)
700			_aSupervisor : Dr. Nosheen Fatima Rana
856			_uhttp://10.250.8.41:8080/xmlui/handle/123456789/31459
942			_2ddc _cTHE
999			_c608367 _d608367